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Sepragen is proud to serve a large base of clients world-wide. It would take a while to list them all, so we've pulled a few well-known names from the list. We also have testimonials from customers regarding positive experiences with our products and services. If you'd like to hear what they're saying, please read on...
Alpha Therapeutic Corporation (Web site)
"This is a personal letter of recommendation for
Sepragen Corporation. We have purchased 6 columns ranging from
10lt to 200lt from Sepragen, and the craftsmanship, service and
quality has been excellent. They have always been willing to go
the extra mile to help and support us through our startup and
maintenance activities until we are successful. Sepragen really puts
their customers first."
Jeffrey Stephens
Project Coordinator
"The QuantaSeps are workhorses in our facility and are used
routinely in development and production. They have enabled us to get
work done with greater consistency in less time. We are satisfied with
the performance of the QuantaSeps and - I might add - with the high
level of care and responsiveness that Sepragen has demonstrated
towards addressing our needs over the years. Their product technology
and service are unmatched."
Guang Qu
Associate Director
Cohesion
Technologies
"At Cohesion we have used a QuantaSep 1000 as a
workhorse in both manufacturing and process development. We are
quite satisfied with its performance. In our hands the QuantaSep
has been a reliable instrument that is also easy to use and
maintain. The flow rate range of the 1000 matched out commercial
requirement for one process and pilot scale for another. It fits
well into smaller processing spaces (critical when working in Palo
Alto). Again, we have been happy with our QuantaSep 1000 and
would be willing to discuss our experience with others"
Lou Sehl, Ph. D.
Senior Scientist and Team Leader
Dade
Behring
"The efficiency of these products, in our hands,
provides a significant advantage over other purification equipment we
have evaluated for the following reasons:
- The QuantaSep software is easy to use and train.
- The QuantaSep allows us to reduce our standard direct hours, thus
reduce our projected costs, by allowing a production chemist to
perform multiple purification tasks simultaneously. This system
eliminates the need to "baby-sit" all the individual
purification steps. With reduced labor costs, the return on investment
is easily less than two years for the QuantaSeps.
- This programmable system insures lot-to-lot consistency, resulting
in consistent elution profiles vs. the built in variability with more
manual operations. A critical advantage for a GMP production process.
- And finally, one unique advantage of this system is its
versatility. We can run both our small and large volume production (5
liter to 200 liter) runs with the change over feature. No other
systems we have investigated have that volume flexibility."
Dennis Gould
Manager, Antibody Manufacturing
Human Genome
Sciences, Inc.
"We have purchased several QuantaSep Systems and use them
routinely in development and manufacturing. They have provided us with
the capability to scale-up quickly and reliably. The robust design and
compact size has enabled us to add productive capacity without waiting
for additional construction.
"The QuantaSep software is easy to learn and use. Automated processing
and report generation have enabled us to get more done with the same
resources. Our quality and consistency have improved, as well. I would
highly recommend the QuantaSep® family of products to anyone."
Mark Oelkuct
Purification Manager
Neose
Technologies, Inc.
"...Neose Technologies, Inc. has purchased equipment from
Sepragen Corporation for installation in a pilot facility. The
equipment included a chromatography pumping skid and some radial flow
columns. This equipment has been received and installed and is
performing up to our expectations.
"The quality of the components and that of the workmanship used in
the fabrication chromatography skid is of top quality and the unit was
delivered on schedule. The radial flow columns were fabricated
and delivered ahead of schedule and their performance is
excellent. A prompt and comprehensive installation service was
provided on site to commission these units."
Kevin Pelin
Director of
Manufacturing Operations
Roche Molecular
Systems (Web site)
"At our company we have a need to produce purified protein at
approximately the 1 gram scale, for use in process development
experiments. We have developed a purification process that uses
Sepragen's QuantaSep automated chromatography system and radial flow
columns (250 ml and 100 ml scale). Using the automated features
of the QuantaSep, our process can be completed during a normal 8 hour
day, from disruption of the cell cake through both chromatography
steps.
"I feel that there are several aspects of the QuantaSep that are
advantageous relative to competitive products. 1) We can run at flow
rates of up to 100 ml/min in our version of the system, and still be
at low pressure. This allows us to use radial flow columns and
means that we can complete our process more rapidly than might
otherwise be true. Secondly, the software is very
straightforward; method editing is easy to master and to remember,
even for researchers who aren't using the system frequently. The
graphical display also makes it very easy monitor the system, and to
run it in manual mode, which is particularly useful during column
washing and equilibration. The system has plenty of flexibility,
allowing users to perform all of the usual chromatography
protocols. The air detection system not only protects the
columns, but allows us to use all of our column loads. Finally,
I think that the simplicity of the design of the liquid flow path
allows the user to easily diagnose any leaks or other problems that
might occur.
"We are quite happy with [the QuantaSep's] performance and
reliability. It does the job it was designed to do. I can
recommend it to anyone seeking an automated chromatography
system."
Keith Bauer
Scientist
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