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QuantaSep® Details
The QuantaSep® 100 pilot/production chromatography system for fluid handling and control is composed of three modules, integrated into a single cabinet with dimensions of 30" width x 24" depth x 18" height and weighing 125 lbs.
- Automates buffer delivery, column switching, fraction collection, based on UV, pH and conductivity
- Graphical, intuitive software "dashboard" for easy operating and training
- Automated GMP reports
Complete batch reports
Event and alarm logs
Chromatograms and calibration history
Data Archival and Security
- Sanitary Flow Path
Low system volume
Minimal dead legs
Precision Hardware
Wier diaphragm valves
Positive displacement pumps
Large dynamic flow range
100:1 turndown ratio for accurate gradients
- Sensors
UV, pH, and conductivity sensors
Integrated flow cell
Optional precolumn pH, and conductivity sensors
Optional second 254 nm UV capability
Pressure, temperature, air, leak
- Safety features
"Active air trap" minimizes "bubble trap dilution"
Optional precolumn filter with differential pressure sensors
Leak and pressure alarms
Built in safety interlocks
Software method checks
Software security prevents unauthorized operation and tampering
The QuantaSep® Family
To meet the growing need for cGMP compatible sanitary
purifications, Sepragen has developed a family of 6 systems
designed to provide purification capability at different scales.
All systems are scalable, and use the same design philosophy and
software. They all automate many routine tasks so that mission
critical project deadlines can be met. Clinical production
capacity can be scaled up quickly within existing space and headcount limitations.
- QuantaSep® 100: Automated chromatography with a flow range of 1-100 ml/min
- QuantaSep® 1000: Automated chromatography with a flow range of 10-1000 ml/min
- QuantaSep® 100LX: A fully automated dual flow range chromatography system
- QuantaSep® 1800: Automated chromatography with a flow range of 20-1800 ml/min
- QuantaSep® 5000: Automated chromatography with a flow range of 50-5000 ml/min
- QuantaSep® 10000: Automated chromatography with a flow range of 100-10000 ml/min NEW!
QuantaSep® Specifications
| |
QSep
100 |
QSep
1000 |
QSep
1000LX |
QSep
1800 |
QSep
5000 |
QSep
10000 |
| Flow Range |
1-100 ml/min |
10-1000 ml/min |
1-100 ml/min
& 10-1000 ml/min |
20-1800 ml/min |
50ml- 5L/min |
100ml- 10L/min |
User Selectable
Buffers |
12 |
12 |
2x12 |
12 |
8 |
8 |
User Selectable
Columns |
3 |
3 |
2x3 |
3 |
1 |
1 |
| User Selectable Fractions |
10 |
10 |
2x10 |
10 |
6 |
6 |
| Hold Up Volume |
7ml |
120 ml |
Low:
18 ml
High:
120 ml |
120 ml |
~650 ml |
1.2 L |
| Component Footprint |
21"x26" x15" |
21"x26" x15" |
21"x26" x15" |
21"x26" x15" |
Mobile Unit;
22"x27" x46.5" |
Mobile Unit;
22"x27" x46.5" |
| Gradient Capability |
5-95% |
5-95% |
5-95% |
5-95% |
5-95% |
5-95% |
| Pressure Rating |
100 psi |
50 psi |
50 psi |
50 psi |
50 psi |
50 psi |
| Tubing |
1/16" ID |
1/4" ID |
Low:
1/16" ID
High:
1/4" ID |
3/8" ID |
1/2" ID |
5/8" ID |
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Chemical Compatability |
| 1M Sodium Hydroxide |
19% Alcohol |
| Operating Temperature |
4oC-25oC |
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Utilities Requirement |
| Power Requirement |
110V |
110/220V; 6Å |
| Air Requirement |
Not Required |
90 psi |
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Wetted Materials of Construction |
| Tubing |
Silicone, Polyethylene, and
Polypropylene |
| Valves & Fittings |
Polypropylene |
| Diaphragms |
PTFE |
| Sensor Components |
Glass, Quartz, 316L Stainless
Steel |
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Components Specifications |
| UV Sensor |
280 nm 0-2 Au
254 nm 0-2 Au (Optional) |
| Conductivity Sensor |
0-200 ms |
| pH Sensor |
1-14 pH |
Air Bubble
Eject Size |
> 0.20" |
| Pressure Sensor |
0-100 psi |
| Leak Sensor |
5 ml leak volume |
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Warranty, Installation and
Support |
| All QuantaSep®'s are backed by
Sepragen's one year limited warranty. Installation and
training, along with IQ/OQ are preformed by Sepragen Service
Group. Preventative maintenance and Total maintenance service
is provided at additional cost. Validation support packages
are also available. |
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