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  QuantaSep® Single UseBenefits and Features | Brochure | Pictures
QuantaSep® 1000 SU / (jump to QuantaSep® 3000 SU) QuantaSep® is a fully integrated system designed to truly automate your purification process. This sanitary bench top system enables you to automatically equilibrate, load, wash, elute and regenerate your chromatography columns. You can also control each step of the purification process based on UV, pH, conductivity, time, column volume, volume, air or % peak max. As the sensors monitor column outflow, the computer reads the information to automatically change buffers and collect fractions, stepping through the method as you programmed it. The computer logs all data such as events, alarms and chromatograms for analysis.
QuantaSep® 1000 Highlights
The QuantaSep® 3000 SU system is mobile, compact, and capable of providing an operating flow range of 30-3000 ml/min. The integrated system has two peristaltic pumps, 8 buffer selection valves, an inline mixer, sensors, and 6 fraction collection valves. Its capabilities include but are not limited to buffer switching, gradient formation, pressure and UV detecting, air sensing and auto air ejection, conductivity and pH sensing pre- and post- column, and forward and reverse flow through column, combined in a powerful easy-to-use software package. The software enables buffer and fraction switching based on process conditions, and activates alarms in the event of overpressure or air leaks. All events are automatically logged, archived, and generated as cGMP reports for record-keeping purchases. The QuantaSep® 3000 SU hardware is composed of control modules and a fluid handling combined into a single ergonomically-designed countertop cabinet. The bench top unit can be cart-mounted for easy mobility. The computer that houses the control software can be integrated with or separated from the system to provide the options of local and remote operation. The system is compatible with 1M NaOH and alcohol for CIP operations and is operable at 4°C for cold room processing.
The fluid handling module contains: 2 pump assemblies consisting of two peristaltic pumps, static mixer, and silicone tubing. These are connected with sanitary clamp connections to pinch valves, UV, pH, leak, conductivity, temperature and pressure sensors, air sensor, air purge valve, sanitary inlets, outlets, and column connections. The components are mounted inside an enclosed stainless steel cabinet with a trough to which a leak detector is attached. Removable Flowpath The flowpath of this system is designed for easy removal. This eliminates the need for cleaning validation. Issues related to cross-contamination in switching columns or products are substantially minimized when the flowpath can simply be replaced. Pinch valves and peristaltic pumps enable easy changing of the pre-fabricated tubing assembly along with the integrated sensor block, which can be easily removed and replaced as well. Controls Module The controls module contains all power supplies, transformers, valve activation pneumatics, brainboards, sensor controls and circuit boards, alarm controls, sensor electronics including A/D and D/A converters, and fuse assembly. The external chart recorder interface, status LED’s, an emergency stop switch, cables, computer interface, fuse blocks, etc. are included as well. Click here for Software Slide Show. Click here to see the specifications for the entire QuantaSep family of products. |
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