Home | Contact Us 

Online Catalog

View our online catalog.
For further information or for a quotation, call 1-510-475-0650 or email us at

How Can We Help You?
Click here to contact us!


QuantaSep® Single Use

Benefits and Features | Brochure | Pictures

*General QuantaSep Information: Specifications | FAQ | Presentation

QuantaSep® 1000 SU / (jump to QuantaSep® 3000 SU)

QuantaSep® is a fully integrated system designed to truly automate your purification process. This sanitary bench top system enables you to automatically equilibrate, load, wash, elute and regenerate your chromatography columns. You can also control each step of the purification process based on UV, pH, conductivity, time, column volume, volume, air or % peak max. As the sensors monitor column outflow, the computer reads the information to automatically change buffers and collect fractions, stepping through the method as you programmed it. The computer logs all data such as events, alarms and chromatograms for analysis.

QuantaSep® 1000 Highlights

  1. Removeable sanitary braided silicon/polypropylene flow-path
  2. Removable pH, conductivity, and UV flow cell
  3. Removeable pressure sensor
  4. Column bypass, forward and reverse flow
  5. Automates buffer delivery, column switching, fraction collection, based on time, volume, UV, pH, and conductivity
  6. Small footprint can fit on bench-top, laminar flow hood or cold room
  7. Large dynamic flow range – up to 1000 ml/min
  8. Small hold-up volume
  9. Graphical, intuitive, 21CFRcompliant software, “dashboard” style for easy operation and training
  10. Automated cGMP reports (including Complete batch reports, Event and logs, and Chromatograms and calibration history
  11. Safety Features include removable active air sensor / automatically ejects air
QuantaSep® 3000 SU

The QuantaSep® 3000 SU system is mobile, compact, and capable of providing an operating flow range of 30-3000 ml/min. The integrated system has two peristaltic pumps, 8 buffer selection valves, an inline mixer, sensors, and 6 fraction collection valves. Its capabilities include but are not limited to buffer switching, gradient formation, pressure and UV detecting, air sensing and auto air ejection, conductivity and pH sensing pre- and post- column, and forward and reverse flow through column, combined in a powerful easy-to-use software package. The software enables buffer and fraction switching based on process conditions, and activates alarms in the event of overpressure or air leaks. All events are automatically logged, archived, and generated as cGMP reports for record-keeping purchases.

The QuantaSep® 3000 SU hardware is composed of control modules and a fluid handling combined into a single ergonomically-designed countertop cabinet. The bench top unit can be cart-mounted for easy mobility. The computer that houses the control software can be integrated with or separated from the system to provide the options of local and remote operation. The system is compatible with 1M NaOH and alcohol for CIP operations and is operable at 4°C for cold room processing.
  1. No Cleaning Validation
  2. Step & Linear Gradients
  3. Reduce Batch Failures by Fail Safe System
  4. Unattended Clinical Production 24/7 Now!
  5. Use Safely on Multiple Products
  6. Generate Automated cGMP Reports
  7. Improve Product Quality & Reliability
Sepragen Quantasep Hardware

The fluid handling module contains: 2 pump assemblies consisting of two peristaltic pumps, static mixer, and silicone tubing. These are connected with sanitary clamp connections to pinch valves, UV, pH, leak, conductivity, temperature and pressure sensors, air sensor, air purge valve, sanitary inlets, outlets, and column connections. The components are mounted inside an enclosed stainless steel cabinet with a trough to which a leak detector is attached.

Removable Flowpath

The flowpath of this system is designed for easy removal. This eliminates the need for cleaning validation. Issues related to cross-contamination in switching columns or products are substantially minimized when the flowpath can simply be replaced. Pinch valves and peristaltic pumps enable easy changing of the pre-fabricated tubing assembly along with the integrated sensor block, which can be easily removed and replaced as well.

Controls Module

The controls module contains all power supplies, transformers, valve activation pneumatics, brainboards, sensor controls and circuit boards, alarm controls, sensor electronics including A/D and D/A converters, and fuse assembly. The external chart recorder interface, status LED’s, an emergency stop switch, cables, computer interface, fuse blocks, etc. are included as well.

Click here for Software Slide Show.

Click here to see the specifications for the entire QuantaSep family of products.


QuantaSep Family Details

QuantaSep® 100

QuantaSep® 1000

QuantaSep® 1000LX

QuantaSep® 1800

QuantaSep® 5000

QuantaSep® 10000

Custom QuantaSep®

QuantaSep® Single Use

Company | Products | News and Events | Contact Us | Terms and Conditions | Privacy Policy © 2020 Sepragen Corporation. All rights reserved. (510) 475-0650