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The Sepralac® Process

 

The Process



The process for producing WPI, alpha-enriched WPI, beta-enriched WPI, lactoferrin, lactoperoxidase and glycomicropeptides is shown in the figure below:

Sepralac Process

In order to capture the proteins on the resin, the pH of the whey is adjusted to a low pH.  This will give all the proteins a positive charge, which will bind it to the negatively charged SepraPrep-S resin. 

The pretreated and pH-adjusted whey is loaded on the column after the column has been equilibrated.  Then the column is washed with water and the proteins are eluted by means of patented 'Opposing Salt and pH' gradients.

The process fractions are processed in an ultra- and diafiltration plant, where the protein is concentrated to 25-27% total solids, while the permeate containing the buffer salt solution is processed in a reverse osmosis plant, concentrating it to 2-3% solids for re-use.

The protein concentrate is dried in a spray dyer, which can be of the tall-form type using an inlet air temperature of 180˚C.


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