The QuantaSep® 100 pilot chromatography system for fluid handling and control is
composed of three modules, integrated into a single cabinet with dimensions of 30"
width x 24" depth x 18" height and weighing 125 lbs. A computer is separate from
the system to provide the option of remote control up to 25 feet away. The system is
compatible with 1M NaOH and 19% alcohol for CIP operations and operable at 4° C for cold room processing.
The fluid handling module contains: Dual stepper motor
controlled pumps, static mixer, PTFE tubing with sanitary clamp connections, diaphragm
shielded solenoid valves, UV, pH, leak, conductivity, temperature and pressure sensors,
air sensor, air purge valve, sanitary inlets, outlets and column connections all enclosed
in a 316 stainless steel cabinet. Total hold-up volume is approximately 7 mls from any one
buffer inlet to any one fraction outlet.
The control and power modules contain: All power supplies,
sensor controls and circuit boards, alarm controls, sensor electronics including A/D and
D/A converters, the external fraction collector interface, external chart recorder
interface, external (user defined detector input) digital display of monitor outputs,
status LED’s, an emergency stop switch, cables, computer interface, fuse blocks, etc.
The system is controlled by an Pentium Personal computer
which includes a minimum of 1.2GB hard drive, 32 MB RAM, 17" SVGA color monitor, 4 MB
V RAM graphics card, mouse, printer port, single 3.5" floppy disk drive and
QuantaSep® 100 control software. Resident DOS 6.0, and Windows 3.1, mouse drivers, etc. (computer and
operating system software specifications are likely to change in line with current
standards).
