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The QuantaSep® 100 pilot/production chromatography system for fluid handling and control is
composed of three modules, integrated into a single cabinet with dimensions of 30"
width x 24" depth x 18" height and weighing 125 lbs. |
A computer is separate from
the system to provide the option of remote control up to 25 feet away. The system is
compatible with 1M NaOH and 19% alcohol for CIP operations and operable at 4° C for cold room processing.
The fluid handling module contains: Dual stepper motor controlled pumps,
static mixer, PTFE tubing with sanitary clamp connections, diaphragm shielded solenoid
valves, UV, pH, leak, conductivity, temperature and pressure sensors, air sensor, air
purge valve, sanitary inlets, outlets and column connections all enclosed in a 316
stainless steel cabinet. Total hold-up volume is approximately 7 mls from any one buffer
inlet to any one fraction outlet.
The control and power modules contain: All power supplies, sensor controls
and circuit boards, alarm controls, sensor electronics including A/D and D/A converters,
the external fraction collector interface, external chart recorder interface, external
(user defined detector input) digital display of monitor outputs, status LED’s, an
emergency stop switch, cables, computer interface, fuse blocks, etc.
The system is controlled by an Pentium Personal computer which includes a
minimum of 4.3GB hard drive, 128 MB RAM, 17" SVGA color monitor, 8 MB V RAM graphics
card, mouse, printer port, single 3.5" floppy disk drive and QuantaSep® 100 control
software. Resident DOS 6.0, and Windows NT, mouse drivers, etc. (computer and operating
system software specifications are likely to change in line with current standards).
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