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QuantaSep® 10000 Process
Chromatography System
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The QuantaSep® 10000 process chromatography system is
mobile, compact and capable of providing an operating flow range of
100ml – 10 liters/min. This sanitary system consisting of disposable
tubing can process a 3000+ liter cell culture batch in one shift! It is
ideal for GMP manufacturing. |
The integrated system has two positive displacement pumps, 8 buffer selection
valves, inline mixer, filters and 6 fractions collection valves. It has
capabilities of buffer switching, gradient formation, feed pre-filtering, air
ejection, conductivity and pH sensing pre and post column, forward and reverse
flow in powerful easy-to-use software package. The software enable buffer
and fraction switching based on process conditions and alarms in the event of
overpressure, air or leaks. All events are logged and archived.
Precision pumping and mixing enables on-line dilution from buffer concentrates.
The QuantaSep® 10000 hardware is composed of a fluid handling and control
modules integrated into a single ergonomically designed counter high
cabinet. The mobile unit is mounted on plastic castors with brakes for
easy mobility. The computer that houses the control software is separated
from the system to provide the option of remote operation. The system is
compatible with 1M NaOH and alcohol for CIP operations and is operable at 4oC
for cold room processing.
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